1776116496
Properties of carbon nano-tubes–Cf/SiC composite by precursor infiltration and pyrolysis process
Materials & Design, 2011
Carbon nanotubes (CNTs) were introduced into the precursor infiltration and pyrolysis (PIP) carbon fiber reinforced silicon carbide matrix (Cf/SiC) composite via the infiltration slurry. The weight fraction of CNTs in the composite was 0.765‰. The fiber–matrix interface coating was prepared through chemical vapor deposition (CVD) process using methyltrichlorosilane (MTS). Effects of the CNTs on mechanical and thermal properties of the composite were evaluated by three-point bending test, single-edge notched beam (SENB) test, and laser flash method. Attributed to the introduction of the small quantity of CNTs, flexural strength and fracture toughness of the Cf/SiC composite both increased by 25%, and thermal conductivity at room temperature increased by 3...
1776116496
Double-shelled nanoporous NiO nanocrystal doped MnO/Ni network for high performance lithium-ion battery
Electrochimica Acta, 2019
In response to the severe blocks of the large volume change and sluggish capacity decay originating from the Lithium ion insertion/extraction in the anodes of Lithium ion batteries, transition metal oxides with high cycle stability are desirable yet extremely challenging for achieving high energy density anodes. Here, we report that a double-shelled NiO nanocrystal-doped MnO layer with robust defects, epitaxially grown on a nanoporous Ni network by simultaneously dealloying and oxidising NiMn alloy, can overcome these challenges to deliver a large capacity with excellent cycle stability. The interconnected core-shell nanoporous structure with robust defects possesses ultrahigh efficient electron/ion transport and a volume buffer. Consequently, the free-stand...
1776116496
Histopathological Evaluation of Dog Sacral Nerve after Chronic Electrical Stimulation for Micturition
Neurosurgery, 1984
Histological evaluations of dog sacral nerves were carried out after stimulation for electromicturition with three types of circumneural electrodes. The use of two types of cuff arrays was associated with a marked buildup of connective tissue around the nerve and filling the lumen of the array. Nerves within the first type of cuff array (having diameters approximately that of the nerve they surrounded) were often extruded from the lumen of the cuff. In some cases, this was accompanied by moderate or marked loss of axons. It is not clear whether this phenomenon was the result of the growth of connective tissue within the cuff or tension on the electrical leads. The damage cannot be attributed to the electrical stimulation because nerves enclosed by nonpulsed ...
1776116496
Aerodynamics of a Single Element Wing in Ground Effect
Journal of Aircraft, 2000
A study was performed of a cambered, double-element, high-lift wing operating in ground effect. The effect of ground proximity and flap setting has been quantified in terms of aerodynamic performance and off-surface flowfield characteristics. Measurements include surface pressure taps, force, surface streaklines, and laser doppier anemometry (LDA). It was found from the Haw visualization that the flow is three-dimensional (3D) towards the wing tip with the main element generating most of the downforce, but retains quasi-2D features near the centre of the wing. However, at large heights the downforce increases asymptotically with a reduction in height, Then there is either a plateau, in the case of a low flap angle, or a reduction in down-force, in the case o...
1776116496
Different catalytic behavior of amorphous and crystalline cobalt tungstate for electrochemical water oxidation
RSC Adv., 2012
Amorphous and crystalline cobalt tungstate (CoWO4) particles, synthesized by solution co-precipitation and subsequent heat treatment, were examined on rotating disk electrodes as water oxidation catalysts. In close to neutral electrolyte (0.2 M Na2WO4, pH 8.0), amorphous CoWO4 exhibited much higher catalytic activity than its crystalline counterpart over an overpotential range of 0.25 to 0.45 V. Calculated Tafel slopes are ∼60 mV per decade for amorphous and ∼110 mV per decade for crystalline electrodes, while the exchange current density of crystalline catalysts is two orders of magnitude higher than that of amorphous. Elemental analysis did not identify substantial composition changes in either amorphous or crystalline films on indium tin oxide (ITO) e...
1776116496
Cytokine Responses in Patients Undergoing Coronary Artery Bypass Surgery after Ischemic Preconditioning
Scandinavian Cardiovascular Journal, 2001
The release of proinflammatory cytokines has been shown to be associated with the development of complications after coronary artery bypass grafting with cardiopulmonary bypass. The purpose of the present study was to establish whether ischemic preconditioning (IP) could limit inflammatory cytokines release in patients undergoing elective coronary artery bypass surgery.Twenty-two patients with multiple-vessel coronary artery disease and stable angina admitted for first-time elective coronary artery bypass surgery were randomized into control or ischemic preconditioning groups. Patients in the IP group were exposed to two cycles of two-minute myocardial ischemia, followed by three minutes of reperfusion, at the beginning of the revascularization operation, be...
1776116496
Evaluation and Gap Analysis of Pediatric Disaster Preparedness Resources
Disaster med. public health prep., 2018
Abstract The goal of this research was to identify, summarize, and evaluate pediatric disaster preparedness resources in the United States and to identify areas that need improvement or further development. Using standard literature, gray literature and website reviews, relevant resources were identified and the 50 most relevant resources were studied in depth. Each resource was given a grade of A, B, or C based on content, format, quality, and thoroughness. These resources were divided into 3 categories: (1) hospital resources, (2) school resources, and (3) training/education resources. Half of the 50 resources (25) were given a grade of A, indicating the highest level of quality and thoroughness, with pertinent information presented in a clear format. Sixt...
1776116496
Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice
Circulation Research, 2016
Activated cardiac fibroblasts (CF) are crucial players in the cardiac damage response; excess fibrosis, however, may result in myocardial stiffening and heart failure development. Inhibition of activated CF has been suggested as a therapeutic strategy in cardiac disease, but whether this truly improves cardiac function is unclear.To study the effect of CF ablation on cardiac remodeling.We characterized subgroups of murine CF by single-cell expression analysis and identified periostin as the marker showing the highest correlation to an activated CF phenotype. We generated bacterial artificial chromosome-transgenic mice allowing tamoxifen-inducible Cre expression in periostin-positive cells as well as their diphtheria toxin-mediated ablation. In the healthy he...
1776116495
A Genome‐wide association study of premolar agenesis in a chinese population
Oral Diseases, 2021
Premolar agenesis is a common subtype of tooth agenesis. Although a genome-wide study (GWAS) has identified some variants involved in tooth agenesis in Europeans, the genetic mutation related to premolar agenesis in the Chinese population remains unclear.We present a GWAS in 218 premolar agenesis cases and 1,222 controls using the Illumina Infinium® Global Screening Array. 5,585,618 single nucleotide polymorphisms (SNPs) were used for tests of associations with premolar agenesis.Four independent SNPs on chromosome 2 were identified as susceptibility loci, including rs147680216, rs79743039, rs60540881, and rs6738629. The genome-wide significant SNP rs147680216 (p = 6.09 × 10-9 ) was predicted to change the structure of the WNT10A protein and interact with h...
1776116495
Gastrointestinal Tract Disorders in Older Age
Canadian Journal of Gastroenterology and Hepatology, 2019
Considering an increase in the life expectancy leading to a rise in the elderly population, it is important to recognize the changes that occur along the process of aging. Gastrointestinal (GI) changes in the elderly are common, and despite some GI disorders being more prevalent in the elderly, there is no GI disease that is limited to this age group. While some changes associated with aging GI system are physiologic, others are pathological and particularly more prevalent among those above age 65 years. This article reviews the most important GI disorders in the elderly that clinicians encounter on a daily basis. We highlight age-related changes of the oral cavity, esophagus, stomach, small and large bowels, and the clinical implications of these changes. W...
1776116495
Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats
Food and Chemical Toxicology, 2009
Cisplatin is one of the most potent chemotherapeutic antitumor drugs. Oxidative stress has been proven to be involved in cisplatin-induced toxicity. Therefore, the present study was undertaken to examine the antioxidant potential of grape seed proanthocyanidin extract (GSPE) against the toxicity of cisplatin in male rats. Cisplatin treated animals revealed a significant elevation in plasma, heart, kidney and liver thiobarbituric acid reactive substances (TBARS), while the activities of antioxidant enzymes (GST, SOD, CAT and GSH-Px, and the levels of glutathione (GSH) were decreased. Aspartate and alanine transaminases (AST and ALT), creatine kinase and lactate dehydrogenase were significantly increased in plasma, while liver AST and ALT were significantly de...
1776116495
Plasma Lipids and Lipoproteins in Vegetarians and Controls
N Engl J Med, 1975
The possible effect of diet on plasma lipids was investigated in a group of vegetarians. Seventy-three men and 43 women who had adhered to a vegetarian diet for an average of three years were studied in the fasting state and compared with a randomly selected group of controls matched for age and sex. Mean cholesterol levels in milligrams per deciliter for vegetarians and controls, respectively, were 126 and 184; low-density lipoprotein, 73 and 118; very-low-density lipoprotein, 11.8 and 17.2; high-density lipoproteins, 42 and 49; and mean triglyceride levels 59 and 86. Mean weight and subscapular skinfold thicknesses were 58 kg and 6 mm for vegetarians and 73 kg and 17 mm for controls. Similar differences in lipid levels were found between subgroups of 42 ve...
1776116495
Complications associated with thoracic pedicle screws in spinal deformity
Eur Spine J, 2010
Thoracic pedicle screws have superior anchoring strength compared with other available fixation techniques. However, these are not universally accepted in many developing countries because of the concerns regarding safety and complications. In addition, there is evidence that pedicle morphology is unique in Chinese patients. The goal of this study was to analyze the complications seen at our institution, while using thoracic pedicle screws for the treatment of thoracic deformity, and to determine the safety of our techniques for the treatment of thoracic deformity in a Chinese population. From 1998 to 2005, there were 208 thoracic deformity patients treated at our institution, 70 of whom were male and 138 were female. Their age ranged from 11 to 55 years (me...
1776116495
Biological control and integrated pest management in organic and conventional systems
Biological Control, 2020
More resilient and sustainable approaches are urgently needed to minimize crop yield losses resulting from pest activity and reduce impacts of pest management on human health and the environment. Increasing implementation of biological approaches, including biological control, biopesticides, biostimulants and pheromones is a mutual high priority for sustainable agriculture leaders and practitioners, including those working in organic agriculture and Integrated Pest Management (IPM). While market and regulatory forces, and pest resistance to conventional pesticides are contributing to growth in implementation of biological approaches, they remain a very small percentage of the overall global crop protection portfolio. Barriers to greater adoption include many...
1776116495
Preferential location of lidocaine and etidocaine in lecithin bilayers as determined by EPR, fluorescence and 2H NMR
Biophysical Chemistry, 2008
We have examined the effect of the uncharged species of lidocaine (LDC) and etidocaine (EDC) on the acyl chain moiety of egg phosphatidylcholine liposomes. Changes in membrane organization caused by both anesthetics were detected through the use of EPR spin labels (5, 7 and 12 doxyl stearic acid methyl ester) or fluorescence probes (4, 6, 10, 16 pyrene-fatty acids). The disturbance caused by the LA was greater when the probes were inserted in more external positions of the acyl chain and decreased towards the hydrophobic core of the membrane. The results indicate a preferential insertion of LDC at the polar interface of the bilayer and in the first half of the acyl chain, for EDC. Additionally, 2H NMR spectra of multilamellar liposomes composed by acyl chain...
1776116495
Adolescent girls and leadership: the impact of confidence, competition, and failure
International Journal of Adolescence and Youth, 2012
The research reported in this paper outlines the impact of confidence, competition, and failure in relation to adolescent girls and leadership behaviour. Focus groups were used as the method of data collection. These focus groups were facilitated electronically using Skype Instant Messaging. Participants were girls from single-sex schools; all were in their final year of schooling and currently held a leadership position. Students were located in schools across Australia, with one school located in South Africa. It was made apparent by this study that girls, at times, lacked confidence in themselves and their ability to enact leadership. Whilst it was acknowledged that girls had a highly competitive nature, especially in the academic and sporting domains, th...
1776116495
QSAR (quantitative structure-activity relationship) studies on local anesthetics
Chem. Rev., 1991
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQSAR (quantitative structure-activity relationship) studies on local anestheticsS. P. GuptaCite this: Chem. Rev. 1991, 91, 6, 1109–1119Publication Date (Print):September 1, 1991Publication History Published online1 May 2002Published inissue 1 September 1991https://doi.org/10.1021/cr00006a001RIGHTS & PERMISSIONSArticle Views656Altmetric-Citations67LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. F...
1776116494
Effects of Lysine Acetylation in a β-Hairpin Peptide: Comparison of an Amide−π and a Cation−π Interaction
J. Am. Chem. Soc., 2006
The acetylation of lysine is a common posttranslational modification of histone proteins, and the interaction of acetylated lysines with aromatic rings is commonly observed in transcriptionally relevant protein-protein interactions. To determine the nature of this interaction and its potential role in protein structure and function, the effect of lysine acetylation on its interaction with tryptophan has been investigated within the context of a beta-hairpin peptide. Acetylation of Lys results in the replacement of a cation-pi interaction with an amide-pi interaction. Despite the loss of positive charge, the interaction energy is not significantly perturbed, although the geometry of interaction is influenced such that the amide NH interacts directly with the ...
1776116494
Nucleobase Pair Analogues 2-Pyridone·Uracil, 2-Pyridone·Thymine, and 2-Pyridone·5-Fluorouracil: Hydrogen-Bond Strengths and Intermolecular Vibrations
J. Phys. Chem. A, 2004
Due to the ultrafast nonradiative decay of the uracil (U), thymine (T), and 5-fluorouracil (5-FU) nucleobases, resolved vibronic spectra of nucleobase dimers with U, T, or 5-FU chromophores have not yet been observed in the gas phase. 2-Pyridone (2PY) is a fluorescent hydrogen-bonding analogue of U with a single N−H donor and CO acceptor group. We report the mass-selected S1 ← S0 vibronic spectra of 2PY·U, 2PY·T, and 2PY·5-FU, revealing properties of their H-bonds free of stacking interactions and backbone constraints. The in-plane H-bond vibrations, ω‘, χ‘, σ‘, are observed for all three dimers; the out-of-plane vibrations β‘, τ‘ and the overtone of the stagger mode 2δ‘ are measured for 2PY·T and 2PY·U. The experimental frequencie...
1776116494
Post-column ethylation for the determination of ionic alkyllead compounds by high-performance liquid chromatography atomic absorption spectrometry
J. Anal. At. Spectrom., 1989
A continuous post-column ethylate generator was used to interface a high-performance liquid chromatographic (HPLC) instrument with a quartz tube (QT) atomic absorption spectrometer for the determination of ionic alkyllead compounds (R3Pb+, R2Pb2+; R = CH3 or C2H5). Analytes were separated as their tetramethylenedithiocarbamate complexes, ethylated, purged from the crude reaction mixture and volatilised into the QT furnace with limits of detection which approached 0.1 ng. A half-replicate 25 factorial design (multivariate analysis) augmented with 11 data points to form a composite design was used to predict alkyllead ethylate response under the influence of five interacting reactor/detector variables. The system, which provided base-line separation of seven i...
1776116494
Antecedents and consequence of employee turnover intention: Empirical evidence from Ghana
10.5267/j.msl, 2015
Article history: Received March 18, 2015 Received in revised format 28 March 2015 Accepted 20 May 2015 Available online May 29 2015 Guided by the theory of reasoned action, this study found support for the hypothesized inverse relationship between work-related factors and employee turnover intention on the one hand, and turnover intention and perceptions of accountable absence legitimacy on the other hand. Specifically, the higher employees’ turnover intent, the lower their perceptions about the accountability of their absence behavior and vice versa. The findings highlight the need to consider turnover intention as a salient construct that plays a dual role, first as a consequence variable to job satisfaction, affective and normative commitments, and next...
1776116494
Psychodynamic Diagnostic Manual, by PDM Task Force
J Analytical Psychology, 2007
Journal of Analytical PsychologyVolume 52, Issue 1 p. 111-114 Book reviews Psychodynamic Diagnostic Manual, by PDM Task Force Soren Ekstrom, Soren Ekstrom New York Association for Analytical PsychologySearch for more papers by this author Soren Ekstrom, Soren Ekstrom New York Association for Analytical PsychologySearch for more papers by this author First published: 22 January 2007 https://doi.org/10.1111/j.1468-5922.2007.00643_2.xCitations: 2Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms a...
1776116494
Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics
Cell Stem Cell, 2024
Gastrulation is a critical stage in embryonic development during which the germ layers are established. Advances in sequencing technologies led to the identification of gene regulatory programs that control the emergence of the germ layers and their derivatives. However, proteome-based studies of early mammalian development are scarce. To overcome this, we utilized gastruloids and a multilayered mass spectrometry-based proteomics approach to investigate the global dynamics of (phospho) protein expression during gastruloid differentiation. Our findings revealed many proteins with temporal expression and unique expression profiles for each germ layer, which we also validated using single-cell proteomics technology. Additionally, we profiled enhancer interactio...
1776116493
The pH Effect on the Growth of Hexagonal and Monoclinic Hydroxyapatite Synthesized by the Hydrothermal Method
Journal of Nanomaterials, 2020
Summary. In the present work, a study of H+ effects on the microstructure and morphology of hydroxyapatite synthesized by the hydrothermal method is reported. The synthesis was realized with pH values of 10, 9.6, 9, 8, and 7. To know the particle size distribution, growth habit, chemical composition, and crystalline phases present, SEM-EDS, XRD, AFM, and FTIR spectroscopy techniques were used and completed with Rietveld analysis. The obtained results showed an important effect of H+ on the morphological and crystallographic characteristics of the hydroxyapatite, demonstrating that the shape and nanoparticle size, as well as the number of crystalline phases, can change depending on the pH during the synthesis. It was observed that there is an increase in the ...
1776116493
Subnational Government and Transnational Networking: The Rationalist Logic of Local Level Europeanization
J of Common Market Studies, 2018
The involvement of subnational actors in EU politics has become an increasingly recognized facet of European integration. However, this highlights an interesting puzzle: subnational authorities in unitary and centralized polities usually lack the formal competence and have limited resources to engage beyond their territorial limits. Why, then, do they engage at the European level? This article addresses this question by exploring their motivations for participation in European transnational networking. These motivations are assessed against a Europeanization framework, exploring whether subnational authorities adopt the ‘logic of consequentialism’ or the ‘logic of appropriateness’ when engaging in transnational networking. The article argues that sub...
1776116493
Intermittent Antibiotic Therapy for Nodular Bronchiectatic
Mycobacterium avium
Complex Lung Disease
Am J Respir Crit Care Med, 2015
Although intermittent, three-times-weekly therapy is recommended for the initial treatment of noncavitary nodular bronchiectatic Mycobacterium avium complex (MAC) lung disease, supporting data are limited.To evaluate the clinical efficacy of intermittent therapy compared with daily therapy for nodular bronchiectatic MAC lung disease.A retrospective cohort study of 217 patients with treatment-naive noncavitary nodular bronchiectatic MAC lung disease. All patients received either daily (n = 99) or intermittent therapy (n = 118) that included clarithromycin or azithromycin, rifampin, and ethambutol.Modification of the initial antibiotic therapy occurred more frequently in the daily therapy group than in the intermittent therapy group (46 vs. 21%; P < 0.001); in...
1776116493
Spectroscopy and structure of 2-hydroxyquinoline
J. Phys. Chem., 1987
Abstract : 2-Hydroxyquinoline (2-H) is known to exist as two tautomeric forms which are nearly equal in energy. These tautomers are referred to as the lactim and lactam (or enol and keto) forms which are interconverted by simple hydrogen atom transfer between the oxygen of the OH group and the ring nitrogen. The spectroscopy of 2HG is of interest because of this tautomerization. Similar proton transfer processes which are important in many biochemical systems may be modeled and elucidated by studying the comparable process in 2HQ: a complete characterization of the dynamics and energetics of tautomerization in 2HQ would therefore not only shed light on the 2HQ system but would serve as a general guide for the understanding of other systems. Keywords: Molecul...
1776116493
Impact of avian and arthropod predation on lepidopteran caterpillar densities and plant productivity in an ephemeral agroecosystem
Ecological Entomology, 2003
Abstract. 1. Most studies evaluating the combined impact of spiders and other predators on herbivore densities in agroecosystems have focused primarily on their trophic connections with invertebrate predators (e.g. carabids, chrysopids); however linkages among spiders and vertebrate predators may also help structure the population dynamics of insect herbivores. A field experiment was conducted to examine the impact of avian and spider predation on lepidopteran caterpillar densities and plant productivity within a Brassica agroecosystem. 2. Arthropod abundance, leaf‐chewing damage, and final plant productivity associated with broccoli, Brassica oleracea L. (var. italica ), were recorded for four treatments: (1) bird present but spiders removed; (2) both bir...
1776116493
Bringing psychology and geography closer
Journal of Environmental Psychology, 1993
In an increasingly competitive academic environment students in pursuit of educational recognition are often vulnerable to the effects of stress. This study explored the relationship of academic stress and wellbeing in 258 university students (50 males and 208 females), aged 18–39 years old. The potential mediating variables of self-compassion, psychological capital, and social support were also explored. Data were gathered through an online survey and analysed using correlation, hierarchical multiple regression analysis and path analysis. Findings revealed self-compassion, psychological capital, and social support to mediate the relationship between academic stress and wellbeing. Research findings could be usefully applied to inform interventions to reduc...
1776116493
Soft x-ray diffraction studies on polymeric Langmuir-Blodgett films
Thin Solid Films, 1991
X-ray reflectivity studies were performed on a series of homopolymers and copolymers with hydrophilic spacers which were prepared on quartz substrates as Langmuir-Blodgett films. Soft X-rays of 1560eV energy were used to enhance spatial resolution without requiring stringent collimation conditions. Specular reflectivity profiles, obtained under θ-2θ conditions, were obtained for a series of multilayers and monolayers of the polymers. Calculated refelctivity profiles, using a multilayer model of the electron density, were in good agreement with the experimental data. The spacing in the Langmuir-Blodgett multilayers was found to increase linearly, to within a first approximation, with the length of the main chain spacer. From the intensity of the peaks in th...
1776116493
Early Functional Outcomes After Prepectoral Breast Reconstruction
Ann Plast Surg, 2019
Introduction Staged, tissue expander-based implant reconstruction continues to be the most common mode of breast reconstruction after mastectomy and has evolved significantly for the past 60 years. Prepectoral acellular dermal matrix (ADM)-assisted breast reconstruction is gaining popularity with complication rates similar to total submuscular and ADM-assisted partially submuscular reconstruction. Ours is among the first reports comparing postoperative pain and early functional outcomes between 2-stage ADM-assisted prepectoral and partial submuscular breast reconstruction. Methods Patients reconstructed with a 2-stage, ADM-assisted prepectoral approach were case matched with patients who had undergone ADM-assisted, partial submuscular reconstruction. Demogra...
1776116493
Effect of Temperature and Relative Humidity on Friction and Wear Properties of Silicone-Based Magnetorheological Elastomer
Tribology Transactions, 2017
In this study, the effect of varying temperature and humidity on the friction and wear properties of a silicone-based isotropic magnetorheological (MR) elastomer were examined with an applied magnetic field. Specifically, MR elastomer specimens were fabricated, and a temperature- and humidity-adjustable reciprocating friction tester was employed. The results indicated that the friction coefficient decreased across all tests when a magnetic field was applied. The friction coefficient increased when the temperature increased and slightly decreased following an increase in relative humidity. The wear depth results also exhibited an increasing pattern as the temperature increased and a decreasing pattern when the relative humidity increased. The surface state ex...
1776116493
Nutrition Status Among HIV‐Positive and HIV‐Negative Inpatients with Pulmonary Tuberculosis
Nut in Clin Prac, 2018
Abstract Background The association between tuberculosis (TB) and malnutrition is well recognized. Considering the risk of mortality due to malnutrition in patients with TB, it is necessary to conduct a thorough nutrition assessment to identify individuals at nutrition risk. The study objective was to assess the nutrition status of hospitalized patients with TB, co‐infected or not by human immunodeficiency virus (HIV). Methods Patients with confirmed diagnosis of TB were included using a cross‐sectional design. Nutrition assessment parameters included: body mass index (BMI), triceps skin‐fold thickness (TSF), bioelectrical impedance analysis (BIA), mid‐upper‐arm circumference (MUAC), mid‐arm muscle circumference (MAMC), food frequency questionnai...
1776116493
Open education as a ‘heterotopia of desire’
Learning, Media and Technology, 2015
The movement towards ‘openness’ in education has tended to position itself as inherently democratising, radical, egalitarian and critical of powerful gatekeepers to learning. While ‘openness’ is often positioned as a critique, I will argue that its mainstream discourses – while appearing to oppose large-scale operations of power – in fact reinforce a fantasy of an all-powerful, panoptic institutional apparatus. The human subject is idealised as capable of generating higher order knowledge without recourse to expertise, a canon of knowledge or scaffolded development. This highlights an inherent contradiction between this movement and critical educational theory which opposes narratives of potential utopian futures, offering theoretical counterposi...
1776116493
Persistent phosphorylation of cyclic amp responsive element-binding protein and activating transcription factor-2 transcription factors following transient cerebral ischemia in rat brain
Neuroscience, 1999
The transcription factors cyclic AMP responsive element-binding protein (CREB) and activating transcription factor-2 were studied in rat brains subjected to 15 min ischemia followed by varied periods of reperfusion using western blot and immunocytochemical analyses. The total amounts of both CREB and activating transcription factor-2 were not altered in the hippocampus after ischemia. In contrast, levels of the phosphorylated forms of both transcription factors decreased during ischemia but rebounded following reperfusion. The phospho-forms of CREB and activating transcription factor-2 showed regional and temporal differences in their expression. Phospho-CREB was increased relative to control levels at 30 min, and continued to increase for at least three day...
1776116493
CASTRO: A NEW COMPRESSIBLE ASTROPHYSICAL SOLVER. III. MULTIGROUP RADIATION HYDRODYNAMICS
ApJS, 2012
We present a formulation for multigroup radiation hydrodynamics that is correct to order O(v/c) using the comoving-frame approach and the flux-limited diffusion approximation. We describe a numerical algorithm for solving the system, implemented in the compressible astrophysics code, CASTRO. CASTRO uses a Eulerian grid with block-structured adaptive mesh refinement based on a nested hierarchy of logically rectangular variable-sized grids with simultaneous refinement in both space and time. In our multigroup radiation solver, the system is split into three parts: one part that couples the radiation and fluid in a hyperbolic subsystem, another part that advects the radiation in frequency space, and a parabolic part that evolves radiation diffusion and source�...
1776116492
Analytical derivation and numerical experiments of degenerate scales for regular N-gon domains in two-dimensional Laplace problems
Applied Mathematics and Computation, 2013
Degenerate scale of a regular N-gon domain is studied by using the boundary element method (BEM) and complex variables. Degenerate scale stems from either the non-uniqueness of BIE using the logarithmic kernel or the conformal radius of unit logarithmic capacity in the complex variables. Analytical formula and numerical results for the degenerate scale are obtained by using the conformal radius and boundary element program, respectively. Analytical formula of the degenerate scale contains the Gamma function for the Gamma contour which can be derived from the Schwarz-Christoffel mapping. Based on the dual BEM, the rank-deficiency (mathematical) mode due to the degenerate scale (mathematics) is imbedded in the left unitary vector for the influence matrices of ...
1776116492
A Smart Sensor Node for the Internet-of-Elevators—Non-Invasive Condition and Fault Monitoring
IEEE Sensors J., 2017
The signal processing scheme of a smart sensor node for the Internet-of-Elevators is presented. The sensor node is a self-contained black box unit only requiring power to be supplied, which enables a cost efficient way to modernize existing elevator systems in terms of condition monitoring capabilities. The sensor node monitors the position of the elevator using an inertial navigation system in conjugation with a simultaneous localization and mapping framework. Features reflecting the elevator system’s operation and health condition are calculated by evaluating the ride quality parameters defined by the ISO 18738-1 standards, the vibration versus frequency spectrum, and the vibration versus position spectrum. Abnormal stops are identified by detecting dece...
1776116492
The influence of topographic parameters on avalanche release dimension and frequency
Cold Regions Science and Technology, 2003
Avalanche hazard zones in Switzerland are defined by the frequency and the impact pressure of a potential avalanche event. Therefore, it is necessary to accurately estimate the release frequency and, related to the frequency, the release area for a specific avalanche track. In order to improve this hazard mapping procedure, a statistical analysis of avalanche releases on well-documented avalanche paths was performed. In the region of Davos, an almost complete database of avalanche events over the last 50 years exists. Using Geographic Information System (GIS) technologies in combination with Digital Elevation Models (DEMs), the recorded avalanche release areas were analysed with respect to topographic characteristics. Topographic parameters like "slope", "co...
1776116492
Kinetic method for the determination of iron(II, III) by its catalytic effect on the oxidation of 3-methyl-2-benzothiazolinone hydrazone with hydrogen peroxide
Analytica Chimica Acta, 1999
The iron catalyzed oxidation reaction of 3-methyl-2-benzothiazolinone hydrazone (MBTH) with hydrogen peroxide was studied kinetically by an initial-rate method. The reaction was followed by measuring the absorbance at 345 nm of the product. According to the kinetic study, a mechanism is proposed which leads to the following rate equation: R0cat=[Fe]0[MBTH][H2O2]P[H+]+Q[H+][H2O2]+S[MBTH][H+][H2O2]+T[MBTH][H2O2]+U[MBTH][H+]+V[MBTH]The optimal conditions for the iron determination by the initial rate procedure were predicted using this rate equation. Under the optimum conditions (9 × 10−3 mol l−1 MBTH, 0.9 mol l−1 hydrogen peroxide, pH 2.7, 40°C), iron(II, III) can be determined in the range 1 to 1000 ng ml−1. The relative standard deviations are 6.2,...
1776116492
Sequent extended Kalman filter capacity estimation method for lithium-ion batteries based on discrete battery aging model and support vector machine
Journal of Energy Storage, 2021
Precise battery capacity estimation plays an important role in the future intelligent battery management system. In this paper, a fusion estimation method based on support vector machine and discrete battery aging model is put forward to enhance the online capacity estimation accuracy of lithium-ion batteries under variable temperature conditions. During the constant current charging process, the support vector machine is developed to estimate the battery capacity, which first trains a single 18650 battery offline and then tests the accuracy of the model using two other batteries of the same type intermittently. Subsequently, the discrete aging model of the battery is proposed to continuously estimate the capacity of the battery. However, unmodelled dynamics...
1776116492
Combined insulin treatment and intense exercise training improved basal cardiac function and Ca2+-cycling proteins expression in type 1 diabetic rats
Appl. Physiol. Nutr. Metab., 2012
This study investigated the effects of 8 weeks of intense exercise training combined with insulin treatment on the Ca 2+ -cycling protein complex expression and their functional consequences on cardiac function in type 1 diabetic rat hearts. Diabetic Wistar rats were randomly assigned into the following groups: received no treatment, insulin-treated diabetic, trained diabetic, and trained insulin-treated diabetic. A control group was also included. Insulin treatment and (or) treadmill intense exercise training were conducted over 8 weeks. Basal cardiac function was evaluated by Langendorff technique. Cardiac expression of the main Ca 2+ -cycling proteins (RyR2, FKBP 12.6, SERCA2, PLB, NCX1) was assessed by Western blot. Diabetes altered basal cardiac functio...
1776116492
A facile fabrication of silver/copper oxide nanocomposite: An innovative entry in photocatalytic and biomedical materials
Photodiagnosis and Photodynamic Therapy, 2020
Abstract In this work, principles and techniques of green chemistry were implemented which exploit environmentally and economically friendly methods using an accessible and non-toxic medium, that is water and ascorbic acid (Vit.C), which leads to the synthesis of silver/ copper oxide (Ag/CuO) nanocomposite. Vit.C was used to furnish the synthesis of excellent and controlled crystalline silver nanoparticles (AgNPs), copper oxide (CuO) and Ag/CuO nanocomposite. Moreover, the structures of all the synthesized nanomaterials were confirmed by wide range of characterization techniques which include UV–vis spectroscopy, FTIR, X-ray diffraction and Electron Diffraction Spectroscopy. However external and internal morphology of newly synthesized nanomaterials were e...
1776116492
Shell-Thickness-Dependent Biexciton Lifetime in Type I and Quasi-Type II CdSe@CdS Core/Shell Quantum Dots
J. Phys. Chem. C, 2018
Suppression of Auger recombination in colloidal quantum dots (QDs) is important for their many applications, ranging from biological tagging, QD lasing, to solar energy conversion. Although it has been reported that the biexciton Auger recombination time of core/shell QDs can be significantly prolonged compared to core-only QDs, a systematic investigation of their dependence on the shell thickness is lacking. In this work, using CdSe@CdS core/shell QDs as a model system, we investigated the shell thickness dependence of biexciton lifetimes in both type I and quasi-type II QDs, prepared using large and small core sizes, respectively. We observe a strong increase of biexciton lifetime with the shell thickness and a larger saturation volume in quasi-type II CdS...
1776116492
Basal plasma hormone levels in depressed perimenopausal women
Psychoneuroendocrinology, 2002
Background: An association between abnormal changes in reproductive endocrine function during the perimenopause and the onset of depression in some women has been suggested but remains controversial. Methods: We examined basal plasma hormone levels in two samples of women with well characterized, first onset depression (major or minor) during the perimenopause and matched comparison groups of asymptomatic women. Results were compared by analysis of variance. Results: No significant diagnosis-related differences were observed in plasma hormone measures of the following: follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), estrone (E1), total (T) or free testosterone (FT), or the E2/LH ratio. We did identify significantly lower morning...
1776116492
Managing side effects of JAK inhibitors for myelofibrosis in clinical practice
Expert Review of Hematology, 2017
Myelofibrosis (MF) is characterized by bone marrow fibrosis, abnormalities in peripheral counts, extramedullary hematopoiesis, splenomegaly and an increased risk of transformation to acute myeloid leukaemia. The disease course is often heterogeneous and management can range from observation alone through to allogeneic stem cell transplantation. As of 2017, the only approved medication for MF remains the JAK Inhibitor (JAKi), ruxolitinib (Novartis Pharmaceuticals, Basel, Switzerland; Incyte, Wilmington, Detroit, USA) although several others have reached advanced stages of clinical trials. Areas covered: In this review, we focus on the management of both common and uncommon side effects arising from the use of currently approved and clinical trial JAKi. Most o...
1776116492
CO2-assisted template synthesis of porous hollow bi-phase γ-/α-Fe2O3 nanoparticles with high sensor property
J. Mater. Chem., 2011
In this contribution, monodisperse porous hollow bi-phase γ-/α-Fe2O3 nanoparticles were successfully fabricated based on hard-template method with using carbon colloids as sacrificial templates. A new concept of assembling one kind of metal oxide with different crystalline structures into a single shell was presented for the first time. The critical procedure of coating carbon cores with a uniform layer of oxide was performed in CO2-expanded ethanol, which is a versatile way to produce high-quality hollow oxide nanoparticles. The formation of the novel bi-phase shell was achieved through combining the reduction ability of carbon cores under inert calcination atmosphere and the unique chemical composition of intermediate-shell formed in CO2-expanded ethanol...
1776116491
Gastro-entérite aiguë chez l’enfant hospitalisé : réduction des durées de réhydratation et d’hospitalisation grâce à la réhydratation par sonde naso-gastrique
Archives de Pédiatrie, 2017
When oral rehydration is not feasible, enteral rehydration via the nasogastric route has been the ESPGHAN recommended method of rehydration since 2008, rather than intravenous rehydration (IVR), for children with acute gastroenteritis. However, these recommendations are rarely followed in France. Since 2011, in case of failure of oral rehydration, enteral rehydration has been used as a first-line therapy in the Children's Emergency Department at the Grenoble-Alpes University Hospital.The aims of the study were to compare the length of the hospital stay, the duration of initial rehydration, and the incidence of complications and failure with the use of enteral nasogastric versus intravenous rehydration.This study compared two cohorts of children (
1776116491
A comprehensive review on thermal management systems for power lithium-ion batteries
Renewable and Sustainable Energy Reviews, 2021
Lithium-ion batteries are extensively utilized in electric vehicles for its high energy density. However, safety problems caused by thermal runaway and performance degradation caused by abnormal temperature must be solved. Electric vehicles must adapt to hot and cold environments, which requires the battery pack to keep good performance at both low and high temperatures. A lot of investigations were reported in the last decade on the thermal management techniques of power batteries. To clarify the problems to be solved in the future, the research progress of battery cooling system and preheating system are thoroughly summarized and classified depending on the heat transfer media. Various thermal management technologies are evaluated from multiple perspective...
1776116491
Baclofen activates two distinct receptors in the rat spinal cord and guinea pig ileum
Neuropharmacology, 1986
Following intrathecal injection, pretreatment with both D-baclofen and 5-aminovaleric acid (5-AV) inhibited the antinociceptive effect of L-baclofen, but homotaurine (3-aminopropane sulphonic acid, APS) was inactive as an antagonist (rank order D-baclofen greater than 5-AV greater than APS = 0). In an established GABAB system, the electrically stimulated guinea pig longitudinal muscle myenteric plexus preparation, APS and 5-AV but not D-baclofen reduced the inhibitory effect of L-baclofen (APS = 5-AV greater than D-baclofen = 0). Receptors with which baclofen interacts in the spinal cord to produce antinociception differ from GABAB receptors with respect to the rank order of potency of antagonists as well as close structural analogs, and these criteria could...
1776116491
Exploring and validating social identification and social exchange-based drivers of hospitality customer loyalty
IJCHM, 2019
Purpose Despite growing academic interest in social identification (e.g. customer brand identification) and social exchange (e.g. commitment/loyalty), little remains known regarding the theoretical interface of these concepts in hospitality sector. Building on this research gap, the purpose of this study is to develop and test a model that explores the effects of brand identification, satisfaction, commitment and trust on customer loyalty toward four and five-star hotels. The authors also explore the mediating role of commitment, satisfaction and trust in the association of brand identification and loyalty. Design/methodology/approach To investigate the objectives of this study, the authors deployed a convenience sample of 345 consumers from four- and five-s...
1776116491
Transient caloric restriction and cancer risk (The Netherlands)
Cancer Causes Control, 2007
Over the past century, many animal experiments have shown that caloric restriction can reduce the risk of cancer, a finding that proved to be highly reproducible. Many papers have been published on its potential for human health, but until know little evidence is available on its actual effects in humans. In Utrecht, The Netherlands, we have been investigating the effects of the 1944-1945 Dutch famine on breast cancer risk factors and breast cancer risk, and paradoxically the relatively short-term famine seemed to be related to increased breast cancer risk in later life. One of the differences between the famine situation and the large body of evidence from animal experiments is the duration of caloric restriction. Almost all animal experiments investigated ...
1776116491
Electron transport studies in space charge layers in vapour-deposited CdSeSiOx films
Thin Solid Films, 1972
Abstract Evaporating an SiO x layer onto a CdSe film generally produces an accumulation layer at the semiconductor-isolator interface, and increases the conductance of the CdSe film. In order to obtain information about carrier transport in this space charge layer, the conductivity and Hall effect were measured between 190° and 460°K on vacuum-annealed CdSe films before and after SiO deposition. The results of measurements are interpreted by means of a simple two-layer model. The essential results of the investigations are as follows. The electron concentration of the interface layer reaches values up to two orders of magnitude higher than in the bulk of the film. The band bending, calculated from the excess interface electron density, is of the order of 0...
1776116491
Social Work Practices in Palliative and End-of-Life Care for Persons Experiencing Homelessness: A Scoping Review
Families in Society: The Journal of Contemporary Social Services, 2018
This article summarizes literature focusing on social work roles in end-of-life care (EOLC) for persons experiencing homelessness. I conducted a scoping review drawing from the framework by Arksey and O’Malley (2005). Included articles were English language, peer-reviewed papers from MEDLINE, Social Work Abstracts, and Social Services Abstracts, published through to May 2018. I reviewed nonscholarly databases and conducted hand searches of reference lists. After applying inclusion criteria, I reviewed 21 articles in full. The selected articles revealed three themes: trusting relationships, collaboration and partnerships, and education, training, and knowledge. EOLC within the mainstream healthcare system holds assumptions that challenge adequate service to...
1776116491
Transformative climate change adaptation: bridging existing approaches with post-foundational insights on justice
Local Environment, 2019
Climate adaptation is a complex policy domain, spanning multiple sectors, scales and actors, and wherein those most at risk have the least power. The influence of linear positivist models of science uptake are proving ineffective in a world with increasingly concentrated wealth and power, institutional barriers, and rapidly growing risks facing the many. A plurality of approaches is needed to better examine those dynamics of climate adaptation which are often invisible in models of science uptake – equity, the value of contestation, path dependency – and to consider how to empower communities to find solutions. In this conceptual paper, we argue that bridging existing positivist and interpretivist methods with insights from post-foundational theory so as...
1776116491
The new challenges of machining Ceramic Matrix Composites (CMCs): Review of surface integrity
International Journal of Machine Tools and Manufacture, 2019
Ceramic Matrix Composites (CMCs) are currently an increasing material choice for several high value and safety-critical components, fact that has recently originated the need of understanding the effect of several machining processes. Due to the complex nature of CMCs - i.e. heterogeneous structure, anisotropic thermal and mechanical behaviour and generally the hard nature of at least one of the constituents (e.g. fibre or matrix) - machining become extremely challenging as the process can yield high mechanical and thermal loads. Furthermore, the orthotropic, brittle and heterogeneous nature of CMCs result in different material removal mechanisms which lead to unique surface defects. Hence, this review paper attempts to provide an informative literature surv...
1776116491
Development of a Loop Mediated Isothermal Amplification for Diagnosis ofAscaris lumbricoidesin Fecal Samples
Journal of Parasitology Research, 2016
Ascaris lumbricoides is a nematode parasite that causes the common tropical infection ascariasis in humans. It is also considered among the neglected tropical diseases. Diagnosis relies mainly on microscopy-based methods which are laborious, are limited by low sensitivity, and require high expertise. We have developed a loop mediated isothermal amplification (LAMP) for diagnosis of ascariasis in fecal samples, based on the first internal transcribed (ITS-1) spacer region of the ribosomal DNA. We used Primer Explorer V4 software to design primers. Ascaris adult and ova were obtained from naturally infected school children, whose parents/guardians gave consent for their participation in the study. Genomic DNA was extracted using alkaline lysis method and ampli...
1776116491
Practical and Methodological Challenges in Validating Community-Based Interventions
Children's Services, 2000
Practical and methodological challenges in conducting research on community-based interventions for adolescent problems are described. First, a conceptual framework for the development of community-based interventions is provided, with an emphasis on the ecological and commonweal advantages of such interventions. Next, important issues that investigators confront when pursuing the dual goals of providing good community-based intervention and conducting rigorous intervention research are addressed. These issues include research design, intervention specification and integrity, participant concerns, changing clinical culture, community challenges, school challenges, and appropriate staffing. Finally, a summary of challenges to conducting good community-based i...
1776116490
Influence of titanium oxide on the surface interactions of MO (M=Cu and Ni)/γ-Al2O3 catalysts
Journal of Solid State Chemistry, 2003
Abstract The influence of titanium oxide on the surface interactions of MO (M=Cu and Ni)/γ-Al2O3 catalysts has been studied by using XRD, LRS and XPS. For the catalysts with titania loadings lower than 0.56 mmol Ti4+/100 m2 Al2O3 (i.e., the dispersion capacity), the dispersion of MO oxides on the surface of γ-Al2O3 support is significantly suppressed by the dispersed Ti4+ ions. The inhibiting effect is dependent on the properties of MO oxides. When titania loadings are considerably higher than the dispersion capacity, MO oxides exhibit a rather stronger interaction with the formed TiO2 particles than the γ-Al2O3 support, and some of the dispersed M2+ ions might be accommodated by the vacant sites on TiO2. Therefore, the catalysts can be considered as th...
1776116490
Esters of apomorphine and N,N-dimethyldopamine as agonists of dopamine receptors in the rat brain in vivo
Neuropharmacology, 1975
Abstract Subcutaneous injections of O,O'-diacetylapomorphine, at doses of 0.1 to 10.0 mg kg , produced stereotyped gnawing behaviour in the rat, indistinguishable from that induced by apomorphine. The dose-response relationship and time course of this effect were similar for the two drugs, although the ester appeared to be somewhat more potent and longer-lasting at higher doses. While apomorphine had no behavioural effects when given orally at doses up to 100 mg kg , diacetylapomorphine produced discernible stereotypy at oral doses as low as 10 mg kg . The injection of diacetylapomorphine into animals previously lesioned electrothermally in the left nigro-striatal tract provoked turning behaviour toward the side contralateral to the lesions, with an effectiv...
1776116490
Matrix isolation IR spectroscopy of tautomeric systems and its theoretical interpretation: 2-hydroxypyridine/2(1H)-pyridinone
J. Phys. Chem., 1992
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMatrix isolation IR spectroscopy of tautomeric systems and its theoretical interpretation: 2-hydroxypyridine/2(1H)-pyridinoneMaciej J. Nowak, Leszek Lapinski, Jan Fulara, Andrzej Les, and Ludwik AdamowiczCite this: J. Phys. Chem. 1992, 96, 4, 1562–1569Publication Date (Print):February 1, 1992Publication History Published online1 May 2002Published inissue 1 February 1992https://pubs.acs.org/doi/10.1021/j100183a015https://doi.org/10.1021/j100183a015research-articleACS PublicationsRequest reuse permissionsArticle Views492Altmetric-Citations176LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individu...
1776116490
Quadruple Hydrogen Bond-Containing A-AB-A Triblock Copolymers: Probing the Influence of Hydrogen Bonding in the Central Block
Molecules, 2021
This work reveals the influence of pendant hydrogen bonding strength and distribution on self-assembly and the resulting thermomechanical properties of A-AB-A triblock copolymers. Reversible addition-fragmentation chain transfer polymerization afforded a library of A-AB-A acrylic triblock copolymers, wherein the A unit contained cytosine acrylate (CyA) or post-functionalized ureido cytosine acrylate (UCyA) and the B unit consisted of n-butyl acrylate (nBA). Differential scanning calorimetry revealed two glass transition temperatures, suggesting microphase-separation in the A-AB-A triblock copolymers. Thermomechanical and morphological analysis revealed the effects of hydrogen bonding distribution and strength on the self-assembly and microphase-separated mor...
1776116490
The Neurobiology of Human Attachments
Trends in Cognitive Sciences, 2017
Attachment bonds are a defining feature of mammals. A conceptual framework on human attachments is presented, integrating insights from animal research with neuroimaging studies. Four mammalian bonds are described, including parent–infant, pair–bonds, peers, and conspecifics, all built upon systems shaped by maternal provisions during sensitive periods, and evolution from rodents to humans is detailed. Bonding is underpinned by crosstalk of oxytocin and dopamine in striatum, combining motivation and vigor with social focus, and their time sensitivity/pulsatility enables reorganization of neural networks. Humans' representation-based attachments are characterized by biobehavioral synchrony and integrate subcortical with cortical networks implicated in rew...
1776116490
Exploring the volatile metabolome of conventional and organic walnut oils by solid-phase microextraction and analysis by GC-MS combined with chemometrics
Food Chemistry, 2021
• Optimization of a HS-SPME-GC-MS methodology to investigate walnut oils’ volatile profile. • Discrimination between organic and conventional walnut oils. • Development of a sPLS-DA model with high prediction accuracy. • Establishment of characteristic volatile markers. It is challenging to establish a correlation between the agronomical practices and the volatile profile of high-value agricultural products. In this study, the volatile metabolome of walnut oils from conventional and organic farming type was explored by HS-SPME-GC-MS. The SPME protocol was optimized after evaluating the effects of extraction time, extraction temperature, and sample mass. The optimum parameters involved the extraction of 0.500 g walnut oil at 40 °C within 60 min. Tw...
1776116490
The Impact of Green Credit Policy on Technological Innovation of Firms in Pollution-Intensive Industries: Evidence from China
Sustainability, 2020
How to promote technological innovation with green finance policy has been a focal topic in the global green finance field in recent years. Using the difference-in-difference approach model, this paper investigated the impact of the Green Credit Guidance (GCG) policy implemented by the Chinese government in 2012 on the technological innovation of firms in pollution-intensive industries. The empirical results indicated that GCG had a negative impact, not only on research and development (R&D) input, but also on innovation output, and the impacts on firms with different property rights and different scales were consistent. Further research showed that GCG reduced the long-term debt of firms in pollution-intensive industries, and then significantly decrease...
1776116490
The interconnection between the structural-mechanical and chemical phenomena accompanying oxidative degradation processes in oriented polypropylene
Polymer Science U.S.S.R., 1975
Mechanical stresses accumulate in the surface layers of the specimen during diffusive oxidation of oriented polypropylene and these stresses, in their turn, affect the chemical mechanism. Degradation of chains in the surface layers of thick specimens occurs to a considerably greater extent than in oriented thin film oxidized under analogous conditions. The yield of hydroperoxide per mole of absorved oxygen is less by a factor of 1·6–1·8 in the thick specimens, and the yield of the number of acts of chain scission is greater by a factor of 1·8–2·6 than in the thin film oxidized under analogous conditions. The observed effects are probably connected with the occurrence of oxidation in the field of the mechanical stresses in the case of the thick specim...
1776116490
Binding of misacylated tRNAs to the ribosomal A site
RNA, 2005
To test whether the ribosome displays specificity for the esterified amino acid and the tRNA body of an aminoacyl-tRNA (aa-tRNA), the stabilities of 4 correctly acylated and 12 misacylated tRNAs in the ribosomal A site were determined. By introducing the GAC (valine) anticodon into each tRNA, a constant anticodon·codon interaction was maintained, thus removing concern that different anticodon·codon strengths might affect the binding of the different aa-tRNAs to the A site. Surprisingly, all 16 aa-tRNAs displayed similar dissociation rate constants from the A site. These results suggest that either the ribosome is not specific for different amino acids and tRNA bodies when intact aa-tRNAs are used or the specificity for the amino acid side chain and tRNA bo...
1776116490
The effect of GMC guidelines on the length of otolaryngological out-patient clinics in a district general hospital
Clin Otolaryngol, 2002
The British Association of Otolaryngologists has laid down guidelines on the length of time that should be allocated to an out-patient consultation. The General Medical Council (GMC) has also produced guidelines as to what is to be discussed with a patient during an out-patient consultation. This study was designed to determine what effect adhering to the GMC's guidelines would have on the length of an out-patient consultation. Out-Patient consultations were timed for patients referred with common otolaryngological complaints. The study was then repeated after the researchers had been given specific instructions on what to discuss with the patients to comply with the GMC guidelines. Consultation times more than doubled after application of the GMC guidelines...
1776116489
Gossip about Coronavirus: Infection status and norm adherence shape social responses
Group Processes & Intergroup Relations, 2021
To stop the spread of the Coronavirus, people must avoid infection risk. Given widespread skepticism regarding information concerning the Coronavirus received from authorities, one potentially important pathway to estimate the infectiousness of one’s group members could be through gossip (i.e., information about an absent target). Infection risk is reflected by both infection status and adherence to social distancing norms. In hypothetical scenarios ( N = 837), participants received gossip that we manipulated to describe a group member’s infection status and/or norm adherence. Results showed people tended to believe gossip and that gossip influenced behavioral intentions to avoid and punish targets of gossip as well as the perception of targets. We concl...
1776116489
Distribution of neutral prilocaine in a phospholipid bilayer: Insights from molecular dynamics simulations
Int J of Quantum Chemistry, 2008
In this work, we report a 20-ns constant pressure molecular dynamics simulation of prilocaine (PLC), an amine–amide local anesthetic, in a hydrated liquid crystal bilayer of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine. The partition of PLC induces the lateral expansion of the bilayer and a concomitant contraction in its thickness. PLC molecules are preferentially found in the hydrophobic acyl chains region, with a maximum probability at ∼12 Å from the center of the bilayer (between the C(4) and C(5) methylene groups). A decrease in the acyl chain segmental order parameter, |SCD|, compared to neat bilayers, is found, in good agreement with experimental 2H-NMR studies. The decrease in |SCD| induced by PLC is attributed to a larger accessible vol...
1776116489
From openness to permeability: reframing open education in terms of positive liberty in the enactment of academic practices
Learning, Media and Technology, 2015
This paper explores the idea of open education, focusing specifically on the concept of openness. Previous discussions of open education are reviewed, using Knox's discussion of ‘unfreedoms' as a critical lens. Contrasts are then drawn with the concept of ‘flexibility’, to illustrate ways in which openness could be developed. This leads to consideration of ideas from sociomaterial theory, focusing on networks and boundaries. A case study is then used to illustrate how these new developments play out empirically. The discussion then elaborates this in terms of ideas about mobility and fluidity. The paper concludes by arguing that the simplistic binary implied by ‘openness’ is largely irrelevant to the academic practices of teachers and learners. It ...
1776116489
Hydrogen Bond Vibrations of 2-Aminopyridine·2-Pyridone, a Watson−Crick Analogue of Adenine·Uracil
J. Am. Chem. Soc., 2002
The 2-aminopyridine.2-pyridone complex (2AP.2PY) is linked by antiparallel N-H.O=C and N-H.N hydrogen bonds, providing a model for the Watson-Crick hydrogen bond configuration of the adenine-thymine and adenine-uracil nucleobase pairs. Mass-selected S(1) S(0) vibronic spectra of the supersonically cooled 2AP.2PY base pair analogue were measured by laser resonant two-photon ionization and emission spectroscopies. The hydrogen bond vibrations nu(2) (buckle, out-of-plane) and the three in-plane vibrations nu(3) (opening), nu(5) (shear), and nu(6) (stretch) were observed in the S(0) and S(1) states, giving detailed information on the stretching and deformation force constants of the (amide)N-H.N(pyridine) and the (amino)N-H.O=C hydrogen bonds. Density funct...
1776116489
Predictors of flight behavior in rural and urban songbirds
The Wilson Journal of Ornithology, 2016
The urban environment poses novel anthropogenic challenges to wildlife. Some species have been noted for changes in their behavior in response to humans and urban-associated activities. Understanding the anthropogenic factors which influence these behavioral changes would contribute significantly to avian conservation in an increasingly urbanized world. We investigated the flight initiation distances (FIDs) and alert distances (ADs) of wild Song Sparrows (Melospiza melodia) and Northern Cardinals (Cardinalis cardinalis) in urban and rural habitats of southwestern Virginia to determine if wild songbirds' tolerances for human approaches differed by species or habitat type (urban or rural). We found Song Sparrows to be more tolerant than Northern Cardinals of h...
1776116489
Sustainable Tourism as a Source of Healthy Tourism
IJERPH, 2020
Even though the World Tourism Organization described Sustainable Tourism as a tourism form that could contribute to the future survival of the industry, the current reality is quite different, since it has not been firmly established in society at expected levels. The present study analyzes which variables drive the consumption of this tourism type, taking tourist awareness as the key element. To this awareness, we must add the current crisis experienced by the tourism industry caused by COVID-19, since it can benefit Sustainable Tourism development, promoting less crowded destinations that favor social distancing. For this, the existing literature on Sustainable Tourism has been examined in order to create a model that highlights the relations among these v...
1776116489
Diversity of dairy goat lactation curves in France
Journal of Dairy Science, 2018
A high level of production at the peak of lactation may be associated with animal health disorders, high feeding costs, and reduced milk supply throughout the year. The objective of this study was to typologize the lactation curves in French dairy goats and analyze the influence of environmental and genetic factors on these curves. The data set consisted of 2,231,720 monthly test-day records of 213,534 French Saanen and Alpine goats recorded between September 2008 and June 2012. First, principal component analysis classified the shape of the lactation curves into 3 principal components: the first component accounted for milk yield level throughout lactation, the second component accounted for lactation persistency, and the third component accounted for milk ...
1776116489
Coffee consumption is correlated with serum cholesterol in middle-aged Finnish men and women.
J Epidemiol Community Health, 1987
The association between coffee consumption and serum cholesterol was studied in a cross-sectional epidemiological study in Finland where the annual per capita consumption of coffee (13.0 kg) is the highest in the world. Coffee consumption was assessed by a questionnaire in a representative population sample of 4744 men and 4495 women aged 25 to 64 years. Serum total cholesterol and HDL-cholesterol concentrations were determined in fresh sera by the enzymatic method. Data on a large number of potential confounding variables were also collected. In the age group 25 to 44 years, the level of serum total cholesterol increased linearly with increasing coffee consumption in both sexes, but in people aged 45 to 64 the peak level of serum cholesterol was found in th...
1776116489
Divalent Metal Ion Coordination by Residue T118 of Anthrax Toxin Receptor 2 Is Not Essential for Protective Antigen Binding
PLoS ONE, 2006
The protective antigen (PA) subunit of anthrax toxin interacts with the integrin-like I domains of either of two cellular receptors, ANTXR1 or ANTXR2. These I domains contain a metal ion-dependent adhesion site (MIDAS) made up of five non-consecutive amino acid residues that coordinate a divalent metal ion that is important for PA-binding. The MIDAS residues of integrin I domains shift depending upon whether the domain exists in a closed (ligand-unbound) or open (ligand-bound) conformation. Of relevance to this study, the MIDAS threonine residue coordinates the metal ion only in the open I domain conformation. Previously it was shown that the MIDAS threonine is essential for PA interaction with ANTXR1, a result consistent with the requirement that the I doma...
1776116489
Advances in computational intelligence (UKCI 2012)
Soft Comput, 2013
This special issue of Soft Computing contains a selection of extended versions of papers presented during the 12th UK Workshop on Computational Intelligence (UKCI 2012) held at Heriot-Watt University (Edinburgh, UK) on 5–7 September, 2012. UKCI is an annual conference which provides a stimulating forum for the academic community to share ideas on theoretical and practical aspects of computational intelligence techniques and is designed to encourage a lively atmosphere for discussing the research findings and future problems, making new contacts and forging collaborations. Over the past eleven editions of UKCI, the list of topics has evolved alongside the field of Computational Intelligence. The current topics of the conference cover all aspects of computat...
1776116488
Thickness Effects of Radio-Frequency-Sputtered Molybdenum Disulfide Films on Soda-Lime Glass Substrates
j nanosci nanotechnol, 2019
Molybdenum disulfide (MoS₂) films were directly formed on soda-lime glass substrates by radio-frequency (RF) sputtering and rapid thermal processing (RTP) to avoid physical exfoliation and transfer process of a MoS₂ layer. The sputtering time was adjusted in the fabrication process and the thickness effects of the MoS₂ films were investigated in terms of structural and electrical characteristics. The surface morphologies were not dependent on the film thickness but on the RF sputtering power after the film was annealed using RTP. The electrical mobility of the MoS₂ film was more dependent on the film thickness at lower RF sputtering powers and low annealing temperatures. An investigation of the E12g and A11g peaks in the Raman spectra revealed that t...
1776116488
Evaluation of the capacity of gel electrophoresis, steadystate and transient state electrofocusing to resolve native human des‐angiotensin‐I‐angiotensinogen from angiotensinogen
Electrophoresis, 1985
The resolution of angiotensinogen (Mr56 800) linked to a decapeptide, angiotensin I (Mr 1295), from the same protein without the decapeptide presents a challenging separation problem. Polyacrylamide gel electrophoresis at an optimized pH of 6.88 is unable to distinguish between the two proteins with statistical significance on the basis of size, but is able to discriminate between them with significance on the basis of their net charge difference. Correspondingly, the proteins are separated in gel electrofocusing with a pI difference of about 0.1 pH unit. For practical purposes, neither the charge separation by gel electrophoresis nor that by steady-state electrofocusing seems sufficiently convenient. By contrast, transient state electrofocusing provides a r...
1776116488
Mechanically robust, self-healing superhydrophobic anti-icing coatings based on a novel fluorinated polyurethane synthesized by a two-step thiol click reaction
Chemical Engineering Journal, 2021
Superhydrophobic coatings have big potential to be used in anti-fouling, drug reduction, anti-icing applications. The fabrication of a robust superhydrophobic coating on hard and smooth substrates still remains challenging. It was reported that fluorinated polyurethane (FPU) was a good candidate for superhydrophobic coatings. However, since the preparation methods of FPU at present are rigid and limited, and the substrate adhesion of FPU is unsatisfied, robust FPU-based superhydrophobic coatings on hard and smooth substrates were rarely reported. In this work, a mechanically robust SiO2-FPU superhydrophobic coating on various substrates was synthesized by a two-step thiol click reaction. The branched fluoroalkyl chains were grafted to the polyurethane backbo...
1776116488
DNA replication licensing proteins: Saints and sinners in cancer
Seminars in Cancer Biology, 2019
DNA replication is all-or-none process in the cell, meaning, once the DNA replication begins it proceeds to completion. Hence, to achieve maximum control of DNA replication, eukaryotic cells employ a multi-subunit initiator protein complex known as “pre-replication complex or DNA replication licensing complex (DNA replication LC). This complex involves multiple proteins which are origin-recognition complex family proteins, cell division cycle–6, chromatin licensing and DNA replication factor 1, and minichromosome maintenance family proteins. Higher-expression of DNA replication LC proteins appears to be an early event during development of cancer since it has been a common hallmark observed in a wide variety of cancers such as oesophageal, laryngeal, pul...
1776116488
Hierarchical Numbering Based Addressing and Stateless Routing Scheme for Wireless Sensor Networks
International Journal of Distributed Sensor Networks, 2009
Due to energy and other relevant constraints, addressing of nodes and data routing techniques in sensor networks differ significantly from other networks. In this article, we present an energy-efficient addressing and stateless routing paradigm for wireless sensor networks. We propose a dynamic and globally unique address allocation scheme for sensors in such a way that these addresses can later be used for data routing. We build a tree like organization of sensors rooted by the sink node based on their transmission adjacency and then set labels on each sensor with a number according to the preorder traversal of the tree from the root. In this addressing process, each sensor keeps necessary information so that they can later route data packets to the destina...
1776116488
A Comparison of NH-π versus Lone Pair Hydrogen Bonding Effects on Carbon Acid pKa Shifts
J. Am. Chem. Soc., 1999
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTA Comparison of NH-π versus Lone Pair Hydrogen Bonding Effects on Carbon Acid pKa ShiftsTimothy S. Snowden, Adrian P. Bisson, and Eric V. AnslynView Author Information The Department of Chemistry and Biochemistry The University of Texas at Austin Austin, Texas 78712 Cite this: J. Am. Chem. Soc. 1999, 121, 26, 6324–6325Publication Date (Web):June 19, 1999Publication History Received1 April 1999Published online19 June 1999Published inissue 1 July 1999https://pubs.acs.org/doi/10.1021/ja991039ahttps://doi.org/10.1021/ja991039arapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views605Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the ...
1776116488
Estimating Sampling Errors in Large-Scale Temperature Averages
J. Climate, 1997
A method is developed for estimating the uncertainty (standard error) of observed regional, hemispheric, and global-mean surface temperature series due to incomplete spatial sampling. Standard errors estimated at the grid-box level [SE2 = S2(1 − r̄)/(1 + (n − 1)r̄)] depend upon three parameters: the number of site records (n) within each box, the average interrecord correlation (r̄) between these sites, and the temporal variability (S2) of each grid-box temperature time series. For boxes without data (n = 0), estimates are made using values of S2 interpolated from neighboring grid boxes. Due to spatial correlation, large-scale standard errors in a regional-mean time series are not simply the average of the grid-box standard errors, but depend upon the...
1776116488
Knowledge-based computational intelligence development for predicting protein secondary structures from sequences
Expert Review of Proteomics, 2008
In the postgenomic age, with the avalanche of protein sequences generated and relatively slow progress in determining their structures by experiments, it is important to develop automated methods to predict the structure of a protein from its sequence. The membrane proteins are a special group in the protein family that accounts for approximately 30% of all proteins; however, solved membrane protein structures only represent less than 1% of known protein structures to date. Although a great success has been achieved for developing computational intelligence techniques to predict secondary structures in both globular and membrane proteins, there is still much challenging work in this regard. In this review article, we firstly summarize the recent progress of ...
1776116487
The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury
Transplantation Reviews, 2012
The primary objective of organ preservation is to deliver a viable graft with minimal risk of impaired postoperative graft function. In current clinical practice, preservation of transplanted organs is based on hypothermia. Organs are flushed and stored using specific preservation solutions to reduce cellular metabolism and prevent cell swelling. However, the ongoing organ donor shortage and consequent expansion of donor criteria to include the use of grafts that would once have been discarded as unsuitable have underlined the need for a technique that prevents any further damage during the preservation period. The principle of normothermic machine perfusion preservation is the maintenance of cellular metabolism in a physiological environment throughout the ...
1776116487
A different kind of social enterprise: social cooperatives and the development of civic capital in Italy
Community Development, 2010
Viewed predominantly as service-based institutions, the contribution of social enterprises to civil society has not received much attention. In the discussion that follows, I draw from a variety of primary sources, including an in person survey of presidents and directors of 140 Italian social cooperatives, as well as in-depth interviews with leaders of the Italian Cooperative Movement, to investigate the capacity of social cooperatives to generate collective benefits for Italian civil society. Combining a social economy framework with emerging conceptual work on civic capital, I analyze the relationship between this unique form of social enterprise and two key challenges to community development in Italy: parochialism and clientelism. By combining systemati...
1776116487
Translation of collision geometry fluctuations into momentum anisotropies in relativistic heavy-ion collisions
Phys. Rev. C, 2010
We develop a systematic framework for the study of the initial collision geometry fluctuations in relativistic heavy-ion collisions and investigate how they evolve through different stages of the fireball history and translate into final particle momentum anisotropies. We find in our event-by-event analysis that only the few lowest momentum anisotropy parameters survive after the hydrodynamical evolution of the system. The geometry of the produced medium is found to be affected by the pre-equilibrium evolution of the medium and the thermal smearing of the discretized event-by-event initial conditions, both of which tend to smear out the spatial anisotropies. We find such effects to be more prominent for higher moments than for lower moments. The correlations...
